GermOnline, a cross-species community knowledgebase on germ cell differentiation
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چکیده
منابع مشابه
GermOnline, a cross-species community knowledgebase on germ cell differentiation
GermOnline provides information and microarray expression data for genes involved in mitosis and meiosis, gamete formation and germ line development across species. The database has been developed, and is being curated and updated, by life scientists in cooperation with bioinformaticists. Information is contributed through an online form using free text, images and the controlled vocabulary dev...
متن کاملDatabase model and specification of GermOnline Release 2.0, a cross-species community annotation knowledgebase on germ cell differentiation
UNLABELLED GermOnline is a web-accessible relational database that enables life scientists to make a significant and sustained contribution to the annotation of genes relevant for the fields of mitosis, meiosis, germ line development and gametogenesis across species. This novel approach to genome annotation includes a platform for knowledge submission and curation as well as microarray data sto...
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1. Germline differentiation of embryonic stem cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 1.1. Early germline fate commitment and PGC development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 1.2. In vitro germ cell differentiation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....
متن کاملThe effect of BMP4 on mouse embryonic stem cell proliferation and differentiation into primordial germ cells
Background and Aim: Artificial gamete production from stem cells is a novel strategy for treatment of infertility. Among various stem cell sources, embryonic stem cells (ESC) can be considered as an appropriate source for in vitro formation of germ cells. In this study we evaluated the effect of BMP4 on proliferation and differentiation of mouse embryonic stem cells into primordial germ cells (...
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Introduction The function of the germ line in all sexually reproducing organisms is to produce gametes that are able to contribute to the next generation (Fig. 1). Thus, like many a great epic film, the germ-cell saga spans generations and addresses such weighty themes as fate, immortality, death and transformation. During the recent meeting (9–13 October 2002) at Cold Spring Harbor Laboratorie...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2004
ISSN: 1362-4962
DOI: 10.1093/nar/gkh055